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Researchers at the University of Illinois at Chicago and two other institutions have unraveled the structure of an important new drug target from the virus that causes SARS, severe acute respiratory s ...


In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood ma ...


A cluster of patients with coronavirus disease 2019 ( COVID-19 ) pneumonia caused by infection with severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ) were successively reported in Wuhan, ...


The coronavirus disease 2019 ( COVID-19 ) virus, emerged in December 2019, has spread rapidly, with cases now confirmed in multiple countries. As of February 16, 2020, the virus has caused 70,548 in ...


Coronavirus disease 2019 ( COVID-19 ) is a pandemic with no specific therapeutic agents and substantial mortality. It is critical to find new treatments. The objective of a study was to determine ...


SARS-CoV-2 uses the angiotensin-converting enzyme ( ACE ) 2 receptor for entry into target cells. ACE2 is predominantly expressed by epithelial cells of the lung, intestine, kidney, heart, and blood ...


The use of convalescent plasma is not new; it was used for severe acute respiratory syndrome ( SARS ), pandemic 2009 influenza A ( H1N1 ), avian influenza A ( H5N1 ), several hemorrhagic fevers such a ...


The detailed results of an analysis of 53 patients hospitalized with severe complications of COVID-19 who were treated with the investigational antiviral Remdesivir on an individual compassionate use ...


Despite limited and conflicting data on the use of Hydroxychloroquine in patients with Covid-19, the FDA ( U.S. Food and Drug Administration ) has authorized the emergency use of this drug when clinic ...


The rapid spread of Coronavirus disease 2019 ( COVID-19 ) caused by severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ) has led to a global pandemic, with infected individuals of all ages r ...


Severe COVID-19 is characterised by interstitial pneumonia and hyperinflammation, with elevated levels of pro-inflammatory cytokines, such as IL-6. Effective treatments are urgently needed, and IL- ...


Since December 2019, novel coronavirus pneumonia ( NCP ) cases have emerged in Wuhan, China, and the 2019 novel coronavirus ( 2019‐nCoV ) was confirmed as the cause of the novel coronavirus pneumonia. ...


SARS-CoV-2 ( Severe Acute Respiratory Syndrome Coronavirus 2 ) causes COVID-19 ( Coronavirus disease 2019 ). The aim of a study was to determine if SARS-CoV-2 RNA in serum at admission correlated wi ...


The clinical features and immune responses of asymptomatic individuals infected with severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ) have not been well described. Researchers have s ...


The first data from a descriptive analysis of a seamless phase 1/2/3 trial of the investigational antibody cocktail REGN-COV2 has reduced viral load and the time to alleviate symptoms in non-hospitali ...